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Published on 09.09.2020
ICMP had a longer Tpeak-Tend-duration and Tpeak-Tend-integral compared to DCMP despite normal parameters of depolarization. This may reflect the different arrhythmogenic morphological substrate and explain why ventricular tachycardias are more common in ICMP.
nICMP (n = 10) | wICMP (n = 12) | nDCMP (n = 10) | wDCMP (n = 10) | |
---|---|---|---|---|
Age (years) | 65 ± 10.5 | 69 ± 4.8 | 57 ± 12.8 | 68 ± 11 |
Male (%) | 60 | 83 | 70 | 60 |
LVEF (%) | 25 ± 5 | 22 ± 7 | 25 ± 6 | 21 ± 6 |
CRT/PM (n) | 1/0 | 6/3 | 1/0 | 6/4 |
ICD | 3 | 4 | 0 | 3 |
Beta-blockers | 2/10 | 9/12 | 6/10 | 8/10 |
Diuretics | 2/10 | 10/12 | 3/10 | 7/10 |
ACE inhibitors / sartans | 1/10 | 9/12 | 7/10 | 8/10 |
Amiodarone | 4/10 | 4/12 | 2/10 | 0 |
Spironolactone | 3/10 | 3/12 | 0 | 5/10 |
nICMP (n = 10) | wICMP (n = 12) | nDCMP (n = 10) | wDCMP (n = 10) | nICMP vs wICMP | nICMP vs nDCMP | nICMP vs wDCMP | wICMP vs wDCMP | nDCMP vs wDCMP | |
---|---|---|---|---|---|---|---|---|---|
QRS duration (ms) | 104 ± 11 | 163 ± 24 | 103 ± 12 | 170 ± 20 | p <0.05 | n.s. | p <0.05 | p <0.05 | p <0.05 |
QRS integral | 30 ± 14 | 79 ± 31 | 34 ± 13 | 87 ± 22 | P <0.05 | n.s. | p <0.05 | p <0.05 | p <0.05 |
JT duration (ms) | 301 ± 34 | 303 ± 52 | 295 ± 55 | 269 ± 30 | n.s. | n.s. | p <0.05 | p <0.05 | p <0.05 |
T duration (ms) | 302 ± 29 | 303 ± 52 | 295 ± 55 | 269 ± 30 | n.s. | n.s. | p <0.05 | n.s. | n.s. |
T integral | 30 ± 9 | 73 ± 29 | 30 ± 15 | 76 ± 28 | p <0.05 | n.s. | p <0.05 | p <0.05 | p <0.05 |
Tp-Te interval (ms) | 109 ± 10 | 124 ± 19 | 76 ± 7& | 126 ± 20 | p <0.05 | p <0.05 | p <0.05 | p <0.05 | p <0.05 |
Tp-Te integral | 10 ± 4 | 24 ± 11 | 7 ± 3 | 30 ± 16 | p <0.05 | n.s. | p <0.05 | p <0.05 | p <0.05 |
QTc duration (ms) | 438 ± 50 | 488 ± 45 | 412 ± 40 | 470 ± 47 | p <0.05 | n.s. | n.s. | p <0.05 | p <0.05 |
Heart rate /min | 73 ± 19 | 68 ± 16 | 70 ± 29 | 70 ± 12 | n.s. | n.s. | n.s. | n.s. | n.s. |
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David Niederseer
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