1 Dugré, N, Lindblad AJ, Perry D, Allan GM, Braschi É, Falk J, et al. Lipid-lowering therapies for cardiovascular disease prevention and management in primary care: PEER umbrella systematic review of systematic reviews. Can Fam Physician. 2023 Oct;69(10):701–11.
2 German CA, Liao JK. Understanding the molecular mechanisms of statin pleiotropic effects. Arch Toxicol. 2023 Jun;97(6):1529–45.
3 Turner RM, Pirmohamed M. Statin-Related Myotoxicity: A Comprehensive Review of Pharmacokinetic, Pharmacogenomic and Muscle Components. J Clin Med. 2019 Dec;9(1):22.
4 Link E, Parish S, Armitage J, Bowman L, Heath S, Matsuda F, et al.; SEARCH Collaborative Group. SLCO1B1 variants and statin-induced myopathy – a genomewide study. N Engl J Med. 2008 Aug;359(8):789–99.
5 Cooper-DeHoff RM, Niemi M, Ramsey LB, Luzum JA, Tarkiainen EK, Straka RJ, et al. The Clinical Pharmacogenetics Implementation Consortium Guideline for SLCO1B1, ABCG2, and CYP2C9 genotypes and Statin-Associated Musculoskeletal Symptoms. Clin Pharmacol Ther. 2022 May;111(5):1007–21.
6 Abd TT, Jacobson TA. Statin-induced myopathy: a review and update. Expert Opin Drug Saf. 2011 May;10(3):373–87.
7 Mach F, Baigent C, Catapano AL, Koskinas KC, Casula M, Badimon L, et al.; ESC Scientific Document Group. 2019 ESC/EAS Guidelines for the management of dyslipidaemias: lipid modification to reduce cardiovascular risk. Eur Heart J. 2020 Jan;41(1):111–88.
8 Magavern EF, Kaski JC, Turner RM, Drexel H, Janmohamed A, Scourfield A, et al. The role of pharmacogenomics in contemporary cardiovascular therapy: a position statement from the European Society of Cardiology Working Group on Cardiovascular Pharmacotherapy. Eur Heart J Cardiovasc Pharmacother. 2022 Jan;8(1):85–99.
9 Carr DF, Francis B, Jorgensen AL, Zhang E, Chinoy H, Heckbert SR, et al. Genomewide Association Study of Statin-Induced Myopathy in Patients Recruited Using the UK Clinical Practice Research Datalink. Clin Pharmacol Ther. 2019 Dec;106(6):1353–61.
10 Centre d’informations thérapeutique et de pharmacovigilance, Service de pharmacologie et toxicologie cliniques, Hôpitaux Universitaires Genève. Interactions medicamenteuses, Cytochromes P450 et P-Glycoproteine (Pgp) [Drug Interactions, Cytochromes P450 and P-Glycoprotein (Pgp)]. 2014 Oct [Accessed 2023 Oct 31]. Available from:
https://www.hug.ch/sites/interhug/files/structures/pharmacologie_et_toxicologie_cliniques/documents/interactions_medicamenteuses_et_cyp450.pdf. French.